In 1958, Maynard would be renamed West Central and Clermont-Elgin would consolidate again, this time with Wadena to form Valley-CEW.

In 1998, Wapsie Valley in Fairbank left for the NICL (North Iowa Cedar League).

[2] North Winneshiek closed its high school upon entering into a whole-grade sharing agreement with Decorah for grades 9–12 in 2002.

Sumner consolidates with Fredericksburg, who was a part of the Iowa Star Conference, to form Sumner-Fredericksburg in 2004.

In 2012 the Upper Iowa Conference expanded south and added Starmont and Edgewood–Colesburg (Ed-Co).

In 2013 North Fayette and Valley-CEW decided to go into a whole-grade sharing agreement, bringing the total of teams in the conference down to 12.