)[8][6] In June 1976, hospital officials established the Upstate Medical Center Foundation to accept donations to help advance patient care to underserved communities.

[9] In November 1994 the new East Wing of Upstate University Hospital is opened and moved into using a staggered occupancy plan.

[10] Ultimately the new children's hospital opened in 2009 at a cost of $150 million with 71 private rooms and 87,000 square feet of space.

[13] In light of the COVID-19 pandemic, on August 19, 2021, SUNY Upstate was awarded $2 million from the Federal Communications Commission (FCC) to help upgrade and support its tele-health infrastructure with a focus on video consults and remote patient monitoring as part of its electronic medical record (EMR) system.

[15] The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–19[4] throughout the region.

Upstate Community Hospital has a medical staff of 460 physicians who provide obstetric, psychiatric, orthopedic, gynecological and medical/surgical services to 12,000 patients each year.

The hospital also offers a wide range of outpatient and community health education services, including nutrition counseling and weight loss programs.

In 2018, NSQIP recognized Upstate University Hospital as a high performer regarding care of high-risk surgical patients.