It has 408 contributing buildings and covers roughly a 33-city block radius in downtown San Francisco.

[2] The Uptown Tenderloin Historic District is an inner-city high-density residential area constructed primarily during the years 1906 until 1941; a period defined by the 1906 earthquake (and fires) and by the Great Depression.

[2] After 1906, the city required fire-resistant construction in the district, which has helped define the boundaries.

[2] There are many building types including boarding houses, hotels, commercial spaces, and apartments.

[2] This article incorporates public domain material from websites or documents of the National Park Service.