Uruguay competed in the Summer Olympic Games for the first time at the 1924 Summer Olympics in Paris, France.

Nicolares was the only Uruguayan boxer to win a bout, reaching the second round before being defeated.

Smoris also reached the second round via bye before losing his first bout.

Six fencers, all men, represented Uruguay in 1924.

Uruguay competed in the Olympic football tournament for the first time in 1924, winning the first of back-to-back gold medals.