Usson (French pronunciation: [ysɔ̃]) is a commune in the Puy-de-Dôme department in Auvergne in central France.

It is a member of Les Plus Beaux Villages de France (The Most Beautiful Villages of France) Association.

Usson's castle was the residence of Margaret of Valois from 1585 to 1605.

According to a 15th-century drawing from the Armorial d'Auvergne, the fortress was large and heavily fortified, with three surrounding walls and 20 towers.

The castle's motto was garde le traître et la dent (lit.