Ust-Nera (Russian: Усть-Нера; Yakut: Уус Ньара, romanized: Ûs Ņara) is an urban locality (an urban-type settlement) and the administrative center of Oymyakonsky District in Yakutia, Russia.

Located in one of the coldest permanently inhabited regions on Earth, Ust-Nera is approximately 870 kilometers (540 mi) northeast of the republic's capital, Yakutsk.

Ust-Nera was founded in 1937 in conjunction with gold mining and exploration in the Indigirka and Kolyma regions.

[citation needed] In the Soviet era, it served as a base for forced labor camps of the gulag.

The Kolyma Highway was extended northwest to Ust-Nera in 1937; this section is now the main route between Yakutsk and Magadan.