[1] A proposal to dam the Drina River at Ustikolina for a hydroelectric power station was rejected by the municipal authorities in October 2006.

[2] Ustikolina has been inhabited since the ancient period, as evidenced by the foundings of Roman coins made of bronze and copper dating from the period between the second and fourth centuries.

Ustikolina is first mentioned in historical sources in the Chronicles of Pope Dukljanin, where it is recorded that the Serbian emperor Časlav 895-896 defeated the Hungarians (Bosnia was a vassal of Hungary during this period) on the Cvilinski field near Ustikolina.

In the local surroundings of Ustikolina there is a necropolis of stećci, which indicates that this area was also inhabited in the Middle Ages by the Bosnian Christians.

In Ustikolina the first known mosque in Bosnia and Herzegovina was built in 1443 or 1448, the original builder is unknown but it was later on named after Turhan Emin-beg.