The former station is located on the east side of South Main Street in the town center, between the road and the tracks of the Providence and Worcester Railroad.

It is a 11⁄2-story brick building with Queen Anne Victorian styling, set on a high granite foundation.

It is a long and roughly rectangular structure, with a tall central portion flanked by lower wings.

[2] The first passenger and freight depot was built in Uxbridge on this site in 1849 by the Providence and Worcester Railroad.

[3] The freight house, located on a long siding near the Capron Mill, served a propane company for several decades but was demolished around 2020.