Uzerche (French pronunciation: [yzɛʁʃ]; Occitan: Usercha) is a commune in the Corrèze department in the Nouvelle-Aquitaine region of central France.

Built on a defensible rocky outcrop in an oxbow of the river Vézère, and located at a medieval crossroads, Uzerche has a long cultural heritage.

In 1996 Uzerche was awarded "village étape" status and, since 2010, has been listed among the towns of France to be worthy of a "plus beaux détour".

The Plateau de Millevaches (a thousand springs), not far from Uzerche, is a natural wetland with its many streams and lakes, forest and heathland.

Uzerche is a hill town, built above a deeply incised meander of the Vézère River; as such it is a natural citadel.

The construction of the gardens along the Vézère, supported by little walls, are as noteworthy as the town's unique position and particular architectural features.

As the rocky ground originally made it unsuitable for agriculture, the view of the lower part of the town is dominated by flowers, orchards and vegetable gardens.

By the 2nd century BC, Gauls had taken advantage of the strategic location of present-day Uzerche—on high ground surrounded by a river—and established a settlement there.

Since before Roman times, Uzerche was situated at the intersection of two trade routes: one connecting Brittany with the Mediterranean Sea, the other allowing people to cross the river Vézère.

After the siege against his half-brother Waifer, Pepin the Short, King of the Francs (751- 768), was convinced of the strategic importance of Uzerche and had no fewer than eighteen towers built in the town, the most impressive being Leocaine, which was established as a royal residence.

Uzerche also had an important religious role, with its own curate, as part of the territorial administrative sub-division of the authority of the Count of Limoges.

In 1095 Pope Urban II travelled to Clermont-Ferrand to prepare for his first crusade and also made a visit to Uzerche in the same year.

The 12th and 13th centuries saw the height of the popularity of the troubadours Gaucelm Faidit and Uc de la Bachellerie who were very well received in Uzerche.

Following the old tradition of giving thanks to St. John for protecting them, people in Uzerche, to this day, hang a walnut branch on their front door every 24 June.

In 1374 Uzerche had three royal lilies added to their Coat of Arms by King Charles V, as a reward for the energetic defence of the city against attacks by the English.

Louis XI visited the city in 1463 and decided to assign half the seats of the royal assize court from his Senechal to Uzerche.

On 30 July 1789 rumour spread in Uzerche that the Count of Artois, brother of Louis XVI, was on his way to the city with 16000 soldiers.

On 5 November 1870, Monsieur Tayac, mayor of Uzerche informed his council of the collapse of the empire and the forming of the Third Republic.

In June 1944, a day after the first D-Day landing in Normandy, General Heinze Lammerding of the SS-Panzer-Division Das Reich gave the order to choose a place between Tulle and Limoges to break the Resistance.

The railway station is situated on the 'Avenue de la gare', the road from Uzerche towards Condat sur Ganaveix.