He enrolled at the University of Miami and began his college baseball career with the Miami Hurricanes before transferring to Oklahoma State University to play for the Oklahoma State Cowboys.
[4] He made his professional debut with the High–A Tri-City Dust Devils, making 6 starts and recording a 5.63 ERA with 15 strikeouts in 16 innings of work.
[5] Mederos began the 2023 season with the Double–A Rocket City Trash Pandas, starting 12 contests and registering a 5.98 ERA with 71 strikeouts across 55+2⁄3 innings pitched.
[6] On June 30, 2023, the Angels promoted Mederos to the major leagues for the first time.
Mederos was optioned to the Triple–A Salt Lake Bees to begin the 2024 season.