Vĩnh Cửu is a rural district of Đồng Nai province in the Southeast region of Vietnam.

[1] The Vĩnh Cửu nature reserve is an area of (mostly secondary) seasonal tropical forest and links directly with Cát Tiên National Park; together they provide contiguous habitat for a number of endangered species including yellow-cheeked gibbons, gaur and Asian elephants.

The Trị An lake (hồ) and dam form a substantial part of this district.

The district is subdivide to a township and 11 rural communes, including:

This article about a location in Đồng Nai Province, Vietnam is a stub.