[2] Born as a village teacher in Tonkin (Northern Vietnam), in the early 1920s, he was soon persuaded by Nguyen Khac Nhu to join the revolutionary path and became an active member of the Việt Nam Dân quốc movement.
He graduated and was granted a commission in the Nationalist Chinese Twentieth Army Corps, where he rose quickly to the rank of brigadier general.
In late December 1949, the Chinese Communist Party defeated the Kuomintang throughout China and forced the remnants of the Việt Nam Quốc Dân Đảng to flee to the Vietnamese border.
In 1952, Vu Hong Khanh served as Minister of Sports and Youth in the Nguyen Van Tam cabinet of the anti-communist State of Vietnam.
Khanh retired to his home village of làng Thổ Tang, modern Vĩnh Tường District, where he died at the age of 95.