Sudheeran started his political career through the Kerala Students Union (KSU), which he served as President from 1971 to 1973.

In 1999 he defeated the renowned Malayalam film Actor Murali with a considerable majority.

In 2009, he refused to contest the elections despite persuasions from party leadership and various social circles, stating that younger politicians need to be given opportunities.

[3] On 10 February 2014, he was selected KPCC President by the High Command of the Indian National Congress.

[4] He was born to Vylopally Sankaran Mama and Girija at a small village named Padiyam in Anthikad on 26 May 1948.