He was a member and served as 6th President of the Malaysian Indian Congress (MIC), a component party of the ruling Barisan Nasional (BN) coalition from June 1973 to his death in October 1979.

Under Manickavasagam's leadership, the MIC was put on a strong footing with buildings, offices and staff in various parts of the country and the party system organised and its capacity to deal with issues enhanced.

The party sponsored the Nesa Multipurpose Cooperative and the MIC Unit Trust as part of its programme for economic ventures, and also set up the MIC Education Fund for members' children and the Malaysian Indian Scholarship Fund for higher education as well as acquiring an Institute for training Indians in technical and trade skills.

This was the time when S. Subramaniam, K. Pathmanaban, a Harvard MBA holder, and several others entered the political arena to infuse new blood into MIC, and Manickavasagam gave them preference.

However, Samy Vellu fought back, literally, and in the 1977 party elections he managed to beat Subramaniam by a mere 26 votes to become the Deputy President of MIC.