The Vachel Lindsay House is located near Springfield's downtown area, at the southwest corner of South 5th and East Edwards Streets.

It is a two-story wood-frame structure, with a front-facing gable roof and clapboarded exterior.

The first floor contains an entry hall, two parlors, library, dining room, kitchen, bathroom, and pantry.

Rooms have been decorated in the late Victorian style, and included the bed in which Vachel Lindsay was born, a desk he built, and the table at which he did much of his writing.

His approach to poetry was unusual and distinctive for the time, using colloquial language, which he delivered in a sing-song chanting style during his public appearances.