Guluzade began his diplomatic career in 1969 as an attache at the Ministry of Foreign Affairs of the USSR and later was promoted to the second secretary of the Soviet Embassy in Egypt.

[1] After service in Cairo, he was transferred to the Middle Eastern Department of the Ministry of Foreign Affairs in Moscow.

In 1987, he was again invited to the Ministry of Foreign Affairs of the USSR and was summoned as a counselor to the Soviet Embassy in Algeria.

From November 1990 until October 1999, Guluzade served as an Advisor and Counselor on Foreign Policy Matters to three consecutive Presidential Administrations of Ayaz Mutallibov, Abulfaz Elchibey and Heydar Aliyev.

He headed numerous delegations from Azerbaijan participating at the OSCE Minsk Group meetings held in Rome, Paris, Vienna, Prague, Geneva, Brussels, Ankara and Moscow.

This caused uproar in a number of well-known newspapers and publications, and triggered sharp reactions in Russia and Iran.