[4][1] Setterfield appeared with the improvisational dance company The Grand Union[6] and in the works of Yvonne Rainer, Robert Wilson, Richard Foreman and JoAnne Akalaitis.

She was featured artist on the WNET/PBS Dance documentary America’s Beyond The Mainstream and in 1987 costarred with Mikhail Baryshnikov in David Gordon's Made in USA for WNET/PBS Great Performances.

She has acted in the work of her son, playwright Ain Gordon, at Soho Rep and Dance Theater Workshop and played herself in his Art, Life & Show Biz at PS 122 and elsewhere.

In film, Setterfield has appeared in the work of Yvonne Rainer and Brian De Palma,[6] and performed the choreography of Graciela Daniele in Woody Allen's Mighty Aphrodite and Everyone Says I Love You.

She played The Old Woman in Eugène Ionesco's The Chairs at London's Barbican Theater, On the Boards in Seattle, and at the Brooklyn Academy of Music's Next Wave Festival.

[11] She also appeared in Jonah Bokaer's Player & Prayer (2008), with Carmen De Lavallade and Gus Solomons Jr.; Anchises (2010); and Occupant (2013).

The award noted that they "are renowned for the poignant humor of their work together – his uncanny sense of irony has found the ideal vehicle in her straitlaced, British facade.