The railway from Valence to Moirans is a 78 km long railway line in southeastern France.

It was built by the PLM and opened on 9 May 1864 to link Valence and Grenoble.

The line is electrified, and is double-track over two-thirds of its length.

[1] In 2011, Réseau Ferré de France announced an €80m contract award to electrify the line from Valence on Paris-Marseille line to Moirans on the Lyon-Grenoble line.

The electrified connection to the LGV Méditerranée allows occasional high-speed services from points south to Grenoble and north.