[2] He initially joined Unicen, before moving to an academy created by his father at the age of five.
[2] He made his senior debut in Liga Tandilense at the age of fifteen, eventually becoming a regular aged sixteen as he featured in both the regional league and Torneo Federal C.[2] In mid-2019, Depietri headed to Santamarina; penning a two-year contract.
[4] After ten total appearances for Santamarina, Depietri received a transfer offer from Major League Soccer side Colorado Rapids in December 2019.
[4][2] However, despite the club's willingness to sell, he rejected the move in order to continue his development with the Aurinegro; stating he wasn't ready to make such a jump.
[4] Depietri, amid rumoured interest from Swiss Challenge League outfit Chiasso, started the subsequent 2020 campaign with a goal against Quilmes on 28 November, which was followed by strikes versus Instituto and Almagro.