Valréas (French pronunciation: [valʁeas]; Occitan: Vauriàs) is a commune in the Vaucluse department in the Provence-Alpes-Côte d'Azur region in southeastern France.

The foundation of the Enclave began in 1317 when Pope John XXII bought Valreas for the papacy of Avignon.

Over the next 150 years or so his successors added to the Enclave by the addition of the small towns of Visan, Richerenches and Grillon.

The boundaries were defined by tall stone markers carrying the coat of arms of the popes.

The present-day boundaries are still delimited by some of these stones, one of which is outside the entrance to the Valreas Tourist office.