Van Dyne is an unincorporated community and census-designated place in the town of Friendship, in Fond du Lac County, Wisconsin, United States.

[3][4] At the 2020 census, its population was 292.

[1] The road traveling north-south through the community was part of the Yellowstone Trail and later Wisconsin Highway 175; it is now a county highway.

The community was first platted by Daniel Van Duyne in 1866, and was a stop for a railroad between Fond du Lac and Oshkosh.

[5][6] A post office has been operating in Van Dyne since 1866.