It includes the neighbourhoods of downtown Vancouver, the West End, Yaletown, False Creek and Stanley Park.

The riding includes the neighbourhoods of Yaletown, the West End, Coal Harbour, Downtown Vancouver, western Strathcona, eastern Kitsilano, and False Creek South.

The heavily urbanized electoral district is by far the most densely populated in Western Canada, with most of its residents living in mid and high rise apartments.

Canada's longest-serving female member of Parliament (MP), Hedy Fry, has represented Vancouver Centre since 1993.

These new boundaries were legally defined in the 2013 representation order, which came into effect upon the call of the 42nd Canadian federal election, scheduled for October 2015.