Vanzone con San Carlo is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont, located about 100 kilometres (62 mi) northeast of Turin and about 35 kilometres (22 mi) west of Verbania.

Vanzone con San Carlo borders the following municipalities: Antrona Schieranco, Bannio Anzino, Calasca-Castiglione, Ceppo Morelli.

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