Disorders in this vast network of blood and lymph vessels can cause a range of health problems that can sometimes become severe, and fatal.

Immobility, active cancer, obesity, traumatic damage and congenital disorders that make clots more likely are all risk factors for deep vein thrombosis.

Intermittent pneumatic compression is a method used to improve venous circulation in cases of edema or in those at risk from a deep vein thrombosis.

Other causes can include an obstructing clot in a hepatic vein (Budd Chiari syndrome) or compression from tumors or tuberculosis lesions.

[13] In a tumor such as infantile hemangioma the mass is soft, and easily compressed, and their coloring is due to the dilated anomalous involved veins.

[14] Vascular disease is a pathological state of large and medium muscular arteries and is triggered by endothelial cell dysfunction.

[23] The process causes thickening of the vessel wall, forming a plaque that consists of proliferating smooth muscle cells, macrophages and lymphocytes.

For example, in the case of a peripheral vascular disease, a physical exam consists of checking blood flow in a patient's legs.

In treating renal artery disease, a 2014 study indicates that balloon angioplasty can improve diastolic blood pressure and potentially reduce antihypertensive drug requirements.