He was born in Apa, Szatmár County, the son of Mihai Lucaciu and Iuliana Toth.
Lucaciu was a member of the National Romanian Party and a co-author of the Transylvanian Memorandum (1892).
As a consequence, Vasile Lucaciu was tried for "homeland betrayal" in Kolozsvár/Cluj in May 1894 and sentenced to five years in prison.
In March 1917, Vasile Lucaciu was a member of a group of exiled Romanian Habsburg subjects who were sent as a delegation to the United States to campaign for Romania's cause.
People can visit today his memorial house [ro] in Șișești, as well as the school, both being now museums.