In 1987–1991, after a military service in the Soviet Army, he worked as a gas electric welder and a foreman at the construction and assembly department in Leningrad.

Khmelnytsky began creating his business empire from traditional sectors, such as real estate and infrastructure, later he started investing in pharmaceutical production, renewable energy and high technologies and innovations.

Explaining the reasons for the sale of Zaporizhstal, Vasyl Khmelnytsky said: «When I realized that China chose the option of steel production development, it became apparent that before long there would be no place left for anyone else in this business»In 2013, the Focus magazine estimated Vasily Khmelnytsky's wealth at $888.6 million (ranked 21st in the 200 Richest People of Ukraine Rating).

At the beginning of 2019 he gave up his power in the ULIE in order to fully concentrate on the development of business and social projects of his holding company UFuture.

[7] At the European Business Summit on 2 June 2016, Vasyl Khmelnytsky presented a strategy for the development of Ukrainian regions exemplified by Bila Tserkva, until 2025.

The project involves attracting $250 million investment, creating seven thousand jobs, an industrial park, a technological cluster and a business incubator.

[9]"It is our intention that our partners view our country not only as a transit zone for the supply of goods to Europe, but also as a platform for the creation of new industries", said Vasyl Khmelnytsky, the First Vice President of ULIE, in Beijing.

[10] In the ULIE Khmelnytsky supervises the promotion of the investment potential of Ukraine, in particular, the attraction of foreign capital and solutions and the development of regional projects.

As of 2018, the UDP company has launched construction projects with an area of more than 3 million square meters and has become one of the largest real estate developers and infrastructure enterprises in the country.

Among its most famous projects are the construction of Ocean Plaza Mall, Novopecherski Lypky, Boulevard of Fountains, RiverStone and Parkove Misto residential complexes.

The entrepreneur is sure that only education and a different way of thinking of Ukrainian citizens can speed up the country's development, helps achieve prosperity and take a proper place in the modern world.