After consistently strong performances, Ćorluka was signed by English Premier League side Manchester City on 2 August 2007.

[10] In the UEFA Cup second qualifying round match second leg, Ćorluka scored the decisive spot kick in the dramatic 4–2 penalty shoot-out victory over Danish minnows Midtjylland after the tie had ended 1–1 on aggregate.

[11] On 1 September 2008, it was announced that Ćorluka had signed for Tottenham Hotspur for a fee of £8.5 million on a six-year contract, joining his fellow Croatian international and best friend Luka Modrić at the club.

[12] During the match against Stoke City on 19 October, Ćorluka was severely injured; kneed under his chin by teammate Heurelho Gomes, he was immediately knocked unconscious.

[13] In the League Cup final on 1 March 2009, Ćorluka scored his and Tottenham's only penalty in the shootout loss to Manchester United, receiving a runners up medal for his efforts.

On 2 February 2011, he started and played the full 90 minutes at right-back ahead of the injured Alan Hutton in the 1–0 victory over Blackburn Rovers at Ewood Park.

[17] Ćorluka made his debut for the club in a 2–2 home draw against VfB Stuttgart at the BayArena on 4 February, playing the full 90 minutes.

[18] In his only Champions League appearance for the club, Ćorluka provided the cross for Michal Kadlec's leveler in the 52nd minute in a 3–1 loss to Barcelona.

Croatia won the match 2–0 and Ćorluka, aged 20 during his debut, entered the game in the second half and satisfied critics with his very good, solid performance against experienced Serie A forwards.

[29] The defender was included for the preliminary squad for Euro 2012 in Poland and Ukraine after impressive performances in his loan spell at Bayer Leverkusen.

[31] On 21 June, he came on as an added-time substitute for Mario Mandžukić in a 3–0 group stage win over Argentina at the Nizhny Novgorod Stadium, earning his 100th cap.

[4][33] On 17 May 2021, Ćorluka was officially presented as Zlatko Dalić's assistant for the upcoming UEFA Euro 2020, succeeding Ivica Olić.