Veliko Središte (Serbian Cyrillic: Велико Средиште; Hungarian: Nagyszered) is a village in Serbia.

It is situated in the Vršac municipality, in the South Banat District, Vojvodina province.

The village has a Serb ethnic majority (77.91%) and its population numbering 1,269 people (2011 census).

In Serbian, the village is known as Veliko Središte (Велико Средиште), in Hungarian as Nagyszered, in Romanian as Srediștea Mare, and in German as Groß-Sredischte.

This South Banat District, Vojvodina location article is a stub.