[2] During the time Ebezâde Abdullah Efendi was Sheikh al-Islam (1708-1710 or 1712–1713), Veliyyüddin was müderris at the madrasa built by his father in the Arabacı Bayezid area of Silivrikapı.
Veliyyüddin came to the attention of Grand Vizier Nevşehirli Damat İbrahim Paşa, who appointed him an inspector of foundations.
In August 1758, he was dismissed and exiled to Manisa because of a petition submitted to Sultan Mustafa III claiming that he had accepted a bribe.
In April 1767, when Dürrîzâde Mustafa Efendi was dismissed as Sheikh al-Islam, Veliyyüddin was appointed a second time.
During one of his terms as Sheikh al-Islam, he established a board of physicians to prevent people from practicing medicine without training.
Veliyyüddin's younger son Hacı Mehmed Emin Efendi was appointed kazasker of Rumelia three times; he died in 1806 and was buried near the Sufi lodge of Şeyh Murad in Eyüp.