The historic town centre with the castle complex is well preserved and is protected by law as an urban monument zone.

A set of ponds is located on the Lovíčský Stream, which flows into the Balinka in the town.

In 1464, the castle was conquered by King George of Poděbrady, and in 1468, the town was ransacked by the army of Matthias Corvinus.

[5] In the 19th century, first factories were built, and the development of the town's industry was also helped by the construction of the railway.

[6] The largest industriual employers based in the town are Draka Kabely (manufacturer of cables and electric wires, part of Prysmian Group), JOPP Automotive (manufacturer of car parts) and POEX Velké Meziříčí (food industry).

[10] Velké Meziříčí lies on the Křižanov–Studenec railway line of local importance.

The original Romanesque-Gothic castle was rebuilt in the Renaissance style in the 16th century and after a fire in 1723, Baroque reconstruction was made.

This Gothic building comes probably from the 12th or 13th century and has a 64 metres (210 ft) high tower open to the public.

The Old Synagogue was built in 1695 and has a Baroque-Neoclassical portal of the main entrance from the late 18th century.