Velzeke-Ruddershove is a double village in the Denderstreek in the province of East Flanders in Belgium, currently part of the municipality of Zottegem.

The settlement of Velzeke dates back from at least the Roman era, when it was a vicus situated at a crossroads in the network of Roman roads in Gallia Belgica.

The archaeological museum of Velzeke exhibits findings from that period.

In 1825, the villages which had grown together where merged in a single municipality.

[3] A hoard of third-century Roman coins has been discovered at Velzeke,[2] including 91 denarii (ranging in date from the reign of Septimius Severus to that of Gordian III) and 93 antoniniani (ranging in date from the reign of Elagabalus to that of Postumus).