The 1st constituency of Vendée (French: Première circonscription de la Vendée) is a French legislative constituency in the Vendéedépartement.

Like the other 576 French constituencies, it elects one MP using the two-round system, with a run-off if no candidate receives over 50% of the vote in the first round.

The 1st Constituency of Vendée is situated in the north of the department including the northern section of La Roche-sur-Yon.

Between this seats establishment on its current boundaries in 1988 and the 2017 this seat consistently centre-right candidates.

For twenty four years the seat was held by Jean-Luc Préel.