The first station in Venlo was opened on November 21, 1865.

The current building dates from 1958 and is a typical Dutch station of the post-war era, featuring a clock tower and a large canopy spanning the front of the station.

There is a bus station for regional and city buses in front of the station, as well as a car park.

The following train services call at this station: Venlo is a border station and therefore sees a significant number of shunting movements.

On several tracks, the catenary can be switched between the 15 kV 16.7 Hz AC used on the Deutsche Bahn network and the 1500 V DC used by Nederlandse Spoorwegen network.