Based on an unproduced 1950s screenplay written by an uncredited Ed Wood, the film was directed and produced by pulp writer Norman Earl Thomson.
The American video release print additionally erroneously featured the credits for a 1969 Philippines production called The Mad Doctor of Blood Island.
The stress of the mission causes him to have a mental breakdown, so his assistant, Dr. Paul Nakamura (Yagi), suggests he take a vacation in Japan at his abandoned luxury resort to recuperate.
In Japan, Dr. Bragan stays at the defunct hotel of Nakamura with Dr. Noriko Hanamura (Kami), the lovely cousin of his coworker who takes on the role of his assistant.
With a potted Venus flytrap he brought from America, the scientist grafts it to a Japanese carnivorous oceanic plant to create a hybrid creature that becomes humanoid and requires the blood of mammals to flourish.
But Bragan is just as obsessive and moody as he was in America, and his behavior causes Noroko to suspect he is going mad, especially when he secretly takes a victim's "heart blood" to feed it.