Verkhneye Isakovo (Russian: Верхнее Исаково) is a rural locality (a village) in Yenangskoye Rural Settlement, Kichmengsko-Gorodetsky District, Vologda Oblast, Russia.

[2] Verkhneye Isakovo is 71 kilometres (44 mi) east of Kichmengsky Gorodok (the district's administrative centre) by road.

Podgorye is the nearest rural locality.

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