The series began its run throughout North America on Discovery Channel in April 2008.

It involves Masterson and the ISOTech crew, along with new recruits and associates, having traveled to Florida; ridding considered residents there of both typical and exotic pests that can be expected of a subtropical environment.

The complete first season was released on DVD by Topics Entertainment on August 10, 2010 in the United States and Canada.

[1] The 4-disc region 1 set titled, Verminators: Extreme Extermination, contained all 13 aired episodes.

It is only available via digital download through Amazon Video in the United States[3] and iTunes in Canada.