He brought the rest of his family to Colorado, and his father and brother, Hugh and Raymond, joined him in the real estate business in 1890.

[1] In the early years of the twentieth century, he and his wife, Mary, sailed for Europe, where they lived for more than a decade in Paris, Rome and the South of France.

[1] Over his career, he was also involved in banking, manufacturing, ranching, land reclamation, and irrigation enterprises in Colorado, Wyoming, and other states.

[2] In addition to his business interests, he also made extensive studies of the Mythologies of Native Americans, especially among the Utes and some of the Puebloan peoples.

[citation needed] The Stoiber-Reed-Humphreys Mansion house in the present Humboldt Street Historic District was owned by the Reeds from about 1912 to 1920.

He left his wife an estate valued at approximately $20 million (equivalent to $351,477,927 in 2023) which she used in the pursuit of various philanthropic endeavors in the Colorado community, such as Margery Reed Hall and construction of a new library on the campus of the University of Denver.