They played in the Class A-Advanced Florida State League from 1980–2008, at which point they relocated to Port Charlotte, Florida as the Charlotte Stone Crabs.

As their names imply, Vero Beach was affiliated with two different Major League Baseball teams during their existence: the Los Angeles Dodgers from 1980–2006 and the Tampa Bay Devil Rays from 2007–2008.

As the Vero Beach Devil Rays, they won the Florida State League championship in 2007.

They played their home games at Holman Stadium, which had served as Los Angeles' spring training facility since 1953.

On August 25, 2008, it was announced that the Vero Beach franchise was sold to Ripken Baseball, which resulted in a relocation of the franchise to Port Charlotte, Florida to become the Charlotte Stone Crabs.