Vicente Abad Santos (Spanish: [ˈbiˈsente aˈβað ˈsantos]: 12 July 1916 – 30 December 1993) was a Filipino who served as an Associate Justice of the Supreme Court of the Philippines.

The two maternal uncles were prominent Filipinos during the American period, Chief Justice José Abad Santos, and his brother Pedro, a leading socialist leader during the Commonwealth era.

After serving briefly as a trial court judge, he joined the faculty of the University of the Philippines College of Law as its dean in 1958.

By 1986, he was asked by the anti-Marcos opposition to swear into office Corazon Aquino's vice-presidential candidate Salvador Laurel at the height of the EDSA Revolution.

Abad Santos and fellow incumbent Justice Claudio Teehankee were the President's first two appointments to the reorganized Supreme Court.