The partido incorporates several smaller neighborhoods, including Olivos, Florida and La Lucila with a total estimated population of 269,420.

Vicente López is renowned for its expansive residential neighborhoods, the Argentine presidential residence, named Quinta de Olivos, and its coastal park along the Río de la Plata.

[3] The partido's name honors Vicente López y Planes, an Argentine writer and politician, author of the lyrics of the Argentine National Anthem, governor of Buenos Aires province (after the fall of Juan Manuel de Rosas) and then President of Argentina succeeding Bernardino Rivadavia.

López y Planes also composed El Triunfo Argentino, an ode to the resistance during the English invasion of Buenos Aires.

At the beginning it was going to be called "Olivos", currently the name of the most important district of Vicente López.