[3] Born in Iași, he studied from 1992 at the Alexandru Ioan Cuza University in the city,[1] graduating in 1999 with an MD degree from the Grigore T. Popa University of Medicine and Pharmacy.
[2] He did his residency in Romania and France, with specialization in cardiovascular and thoracic surgery.
After working for over 10 years in hospitals in France, Great Britain, Denmark, Scotland, Germany, Quebec, and the United States, Costache decided to return to Romania in 2014, becoming an Associate Professor at the Lucian Blaga University of Sibiu.
[1][2] Since 2015 he is President of the Cardiovascular Surgery Commission at the Ministry of Health.
He is also a member of the French Society of Thoracic and Cardiovascular Surgery.