He completed his novitiate with the Missionary Oblates of Mary Immaculate in Kaluthara (1959), then the studies of philosophy and theology at Our Lady of Sri Lanka Seminary in Kandy (1960–1966).
He was parish priest in Gojra for a third time from 1992–1993; Assistant in the formation house of the Oblates in Karachi, 1993–1997 and First Counselor of the OMI Delegation in Pakistan from 1997-2001.
[6] He was consecrated Bishop at Saint Patrick's Cathedral, Karachi on 16 July 2010 by the apostolic nuncio to Pakistan Archbishop Adolfo Tito Yllana.
The Principal Co-Consecrators were Archbishop Evarist Pinto of Karachi and Bishop Max John Rodrigues of Hyderabad.
The prime minister of Pakistan Imran Khan has said that his government will look into “the plight of the oppressed and weakest segments of the society, including minorities.”[7] He died on December 12, 2020, because of a heart attack.
[8] The funeral of Bishop Gnanapragasam took place at Holy Rosary Cathedral, Quetta on December 15, 2020.