Victoria Nonyamezelo Mxenge (1 January 1942, in King William's Town, Eastern Cape – 1 August 1985, in Umlazi, Durban, Natal) was a South African anti-apartheid activist; she was trained as a nurse and midwife, and later began practising law.

She became a member of the Release Nelson Mandela Committee (RMC), sat on the executive of the National Organisation of Women (NOW) and the Natal Treasurer of the UDF.

"[2] Her funeral which was held on 11 August 1985 in Rayi Village near King William's Town[9] was attended by 10,000 people, and letters of condolence were received from Nelson Mandela and Oliver Tambo amongst others.

The Truth and Reconciliation Commission (TRC) Report on the assassination of Victoria Mxenge documents that Marvin Sefako (alias Bongi Raymond Malinga) was allegedly recruited by the security branch and that Brigadier Peter Swanepoel was his handler.

In October 2005, the South African Ministry of the Environment launched the third and final Lillian Ngoyi-class patrol vessels named Victoria Mxenge in her honor.

[2] In 2006 both Victoria Mxenge and her husband were posthumously awarded the Order of Luthuli in Silver for excellent contributions to the field of law and sacrifices made in the fight against apartheid in South Africa.

[5] On 20 August 2017, the KwaZulu-Natal government and eThekwini Municipality unveiled statues in honour of Griffiths and Victoria Mxenge in uMlazi, south of Durban.

[12] Victoria Mxenge was mentioned alongside other anti-apartheid activists Steve Biko and Neil Aggett in the 1987 song Asimbonanga by the South African band Savuka, composed by Johnny Clegg and dedicated to Nelson Mandela.