While Vigna Randanini are just one of the two Jewish catacombs in Rome open to the public, they can only be visited by appointment.

[3] The entrance reused a pagan building, to which was added a vaulted ceiling and a floor mosaic with black and white tiles.

[4] The catacombs, which are on two levels between 5 and 16.3 metres below the surface,[2] were used between the 2nd and 4th centuries, with the maximum number of interments at the end of that period.

[4] Some painted cubicles depict flower motifs and animals but also subjects typical of the Jewish faith such as the seven-branch candelabrum.

These decorations suggest to some researchers that the tunnels had previous pagan occupants and may have been reused by the Jews.