Vilhelm Andreas Wexelsen (5 June 1849 – 9 July 1909) was a Norwegian bishop and politician for the Liberal Party.

He served five terms in the Norwegian Parliament, was Minister of Education and Church Affairs from 1891 to 1892 and from 1898 to 1903 and bishop of Nidaros from 1905 to 1909.

Wexelsen was elected to the Norwegian Parliament in 1883, representing the constituency of Nordre Trondhjems Amt.

[2] On 6 March 1891, when the first cabinet Steen assumed office, Wexelsen was appointed Minister of Education and Church Affairs.

He was re-elected for a fifth term in 1898, this time representing the constituency Trondhjem og Levanger, but on 17 February 1898 he returned as Minister of Education and Church Affairs as a part of the new second cabinet Steen.