Villa Crespo is a middle class neighborhood in Buenos Aires, Argentina, located in the geographical center of the city.

This trade name, caused a reaction from the Neighborhood Association and Historical Studies at the Ombudsman of the city of Buenos Aires.

Under Juan B. Justo avenue runs the Maldonado waterstream, culverted to prevent major floods.

Villa Crespo has been traditionally associated with the Jewish community, hosting several synagogues, Hebrew schools and youth movements.

Until the 1980s, it had a clothing commercial centre in Scalabrini Ortiz Avenue (previously named Canning), but this has lost its strength over the years.