In 1778 the count of Vedano, Giambattista Gallarati Scotti, sold it (with the neighbouring building, today known as Palazzo Ghirlanda-Silva) to Gaspare Ghirlanda who probably started the reconstruction and the decorative works of which many traces remain.

The building, because of its heritage status and the recent transformation into a nursing home, has been frequently modified for practical and sanitary reasons: two shells and an extension were demolished in 1963.

Through the grand staircase to the first floor, there is a large "Arts and crafts" fresco by Max Squillace, Franco Ghezzi and Gian Mario Mariani.

The family, in a social context, is depicted by a man who gives to a woman, lying on the large hand of mother earth, a wheat seed as a sign of fertility.

In the second half of the nineteenth century it was enlarged and transformed into a classical romantic garden with a man-made hill, winding paths, irregularly set shrubs, rocks bordering the flower-beds, allées and fencing.

Of particular note are the monumental hackberry in front of the De Pisis greenhouse, the magnificent Sophora japonica and the historic thicket of bamboo.

Villa Fiorita became a psychiatric nursing home, and between 1949 and 1956 it hosted the painter Filippo de Pisis (1896-1956) of Ferrara who used the greenhouse as an office.