Villa Gobernador Gálvez is a city in the province of Santa Fe, Argentina, located on the western ravine of the Paraná River, within the metropolitan area of Greater Rosario.

The city was founded by an Italian immigrant, engineer Enrico Mosconi, on 25 February 1888 (he was the father of military engineer General Enrique Mosconi, first director of the YPF state oil company).

Dr. José Gálvez, governor of Santa Fe since 1886, hired Mosconi to trace the railway system that would link this province to Mendoza.

For this purpose Mosconi acquired land, and upon authorization by the governor, set up a village, populated mostly by other immigrants from Italy and Spain.

The town was declared a city by Governor Carlos Sylvestre Begnis on 12 April 1962.