The Villalobos Brothers have accompanied and collaborated with many international artists, including Morley, Paloma San Basilio, Paddy Moloney and The Chieftains,[citation needed] Eddie Palmieri, Graciela, Dolly Parton, León Gieco, Leni Stern, César Camargo Mariano, Lila Downs, Richie Ray & Bobby Cruz, Pierre Boulez, Alberto Vázquez, Johnny Ventura, Dan Zanes and Rafael Escalona.

[1] From 1990 to 2000 they studied classical violin with Carlos Marrufo Gurrutia,[2] and composition and counterpoint with Eugeniusz Sleziak Kandora,[3] Roberto Lira López, and Ryszard Siwy Machalica.

[4][5] The Villalobos Brothers were considered child prodigies[6] and had early soloist debuts with the Xalapa Symphony Orchestra[7] playing the Sibelius, Brahms, and Saint-Saëns violin concertos.

Jarocho describes the unique style as being created by the people and culture of the southern coastal plain of Veracruz, who for more than two centuries have shaped a distinctive regional music which intertwines fundamentals of jazz, rock and blues.

[19] Most of their original music features complex patterns of interwoven three-violin harmonies, intricate call-and-response arrangements, and lyrical melodies carried out by one of the brothers as the other two reinforce it in counterpoint.

[22] On 17 December 2006, the Villalobos Brothers were invited back to Carnegie Hall,[23][24] this time leading the music program for Calpulli Mexican Dance Company's[25] production at the Isaac Stern Auditorium involving over a hundred dancers and musicians and with the special participation of the Mariachi Academy of New York.

[12][23][21] They arranged and performed the music of Grammy winners Graciela, Paloma San Basilio, León Gieco, César Camargo Mariano, Richie Ray & Bobby Cruz, Alberto Vázquez, Johnny Ventura and Rafael Escalona.

[12] In 2005 Ernesto Villalobos and Adam Feder led a candlelit vigil at the children's barracks inside the Auschwitz-Birkenau Memorial and Museum as part of Bernie Glassman's Bearing Witness Zen Peacemakers retreat 2005 in Oświęcim, Poland.

Later that year, they also toured the West Coast of the US as part of the show Holiday House Party With Dan Zanes and Friends, ending with a three-week residency at the New Victory Theater on Broadway.