Ville-la-Grand (French pronunciation: [vil la ɡʁɑ̃]; Arpitan: Vela-la-Grand) is a commune in the Haute-Savoie department in the Auvergne-Rhône-Alpes region in south-eastern France.

Ville-la-Grand was founded during the Roman Republic, from around 48BC to 44BC, with the establishment of a villa by a rich patrician or a simple veteran rewarded by Julius Caesar, whereas the nobles of the time were located at Allobroges.

Given back to the Duchy of Savoy in 1814, the commune lost some of his territory because of the Treaty of Turin when the villages of Présinge, Puplinge, the hamlets of "la Louvière" and "Carra" are transferred to the canton of Geneva.

As part of an imperial decree from 22 December of the same year, the rail station of Annemasse is built on land owned by the city of Ville-La-Grand to realize a railway to Thonon.

On 8 July 1944, six members of the French Resistance were killed by German forces on the "lieu-dit" « sur les côtes », including Marianne Cohn.